news center

Cancer blocker

Cancer blocker

作者:郭鲥  时间:2019-03-06 12:06:02  人气:

BLOCKING the enzyme telomerase can stop cancers forming, says Maria Blasco and her colleagues at the National Biotechnology Centre in Madrid. Telomerase lengthens the “fuses”, or telomeres, on the ends of chromosomes, allowing cancer cells to divide indefinitely. Without it, these fuses should burn down, stopping division. But attempts to control cancer by blocking telomerase have had mixed results. Mice that lack telomerase still get tumours because, unlike humans, their telomeres are very long. So Blasco’s team cross-bred mice without the telomerase gene until they had very short telomeres. When exposed to carcinogens,